Endocrine Abstracts

Introduction: The Quervain’s disease is an infrequent subacute thyroiditis (ST) that results in granulomatous infiltration of the gland’s parenchyma. Is usually diagnosed clinically based on cervical pain, systemic symptoms, altered thyroid function tests (TFTs) and history of upper respiratory tract infection. It is a benign self-limited condition that may share US features with malignancy which may result in improper therapy, including lobectomy.<p class="abs...

Introduction: Cushing syndrome is a complex disease with multisystemic manifestations. It includes skin and connective tissue abnormalities, in which glucocorticoids reduce the synthesis and production of collagen, resulting in skin thinning, subcutaneous vascular tissue frailty and mucocutaneous bleeding. Case report: A 59-year-old woman with history of hypertension, type 2 diabetes, hypercholesterolemia, and chronic kidney disease, was admitted to the ...

Introduction: Adrenal incidentalomas (AIs) are defined as adrenal masses measuring 10 mm or more in diameter, incidentally discovered on imaging exams performed for a non-adrenal disorder. The aim of this study is to provide a clinical and imagiological characterization of patients diagnosed with AIs followed in our institution.Methods: We conducted an observational and retrospective study that included patients with AIs evaluated at our institution betw...

Introduction: A simple linear anthropometric linear equation for total body fat quantification in adults was recently selected as the best of 365 anthropometric indexes in the American population. The authors intend to evaluate the correlation between the relative fat mass (RFM) equation and body fat determination by electric bioimpedance (EB) and compare it with BMI.Material/methods: Retrospective, cross-sectional, observational study that selected all ...

Background and aims: Hypoglycemia is a common complication of diabetes treatment and it’s associated with poor outcomes. A link between severe hypoglycemia and renal dysfunction was suggested. No studies evaluated the impact of hypoglycemia of inpatients in microvascular or macrovascular complications. The aim of our work was to study the evolution of renal function between admission and final visit, and the impact of nephropathy in the presence of hypoglycemia in inpatie...

Introduction: Testosterone treatment in patients with hypogonadism has been associated with cardiovascular and prostatic complications.Objective: To describe the evolution of analytical parameters associated to the complications of testosterone treatment in a male population with hypogonadism treated with testosterone. Methods A retrospective, longitudinal study in which the clinical data of male adults with hypogonadism under intramuscular testosterone ...

Background: Amiodarone is an antiarrhytmic drug used mainly in atrial fibrillation. Amiodarone-induced thyrotoxicosis (AIT) is less common than hypothyroidism, but it represents a true therapeutic challenge. AIT can be due iodine load (type 1) or a destructive thyroiditis (type 2).Methods: Retrospective study of patients with AIT, diagnosed between 2010 and 2015, in a central hospital. We reviewed medical records regarding age, gender, amiodarone therapy...

Background & objectives: Vibration perception threshold (VPT) is the gold standard for diagnosis of diabetic peripheral neuropathy. The relationship between symptom severity and VPT remains to be determined. This study evaluated the diagnostic utility of symptoms using the NTSS-6 symptom score vis a vis Bio-thesiometry.Methods: diabetic patients with symptoms suggestive of peripheral neuropathy and 40 apparently healthy controls were studied. Detaile...

Background: Self-monitoring of blood glucose (SMBG), an important tool in diabetes management help patients achieve and maintain target glycaemic levels hence reducing complications. SMBG is usually done with glucose meters which are affordable, portable and easy to use. Significant variations sometimes observed in glucose meter readings necessitated this study. We evaluated the accuracy of glucose meters used routinely in our unit using ISO 15197 guideline.<p class="abste...

GH-secreting and non-functioning pituitary tumors are clinically distinct, usually benign but potentially locally aggressive lesions originating from the replication of a single mutated pituitary cell. As for the underlying genetic and epigenetic alterations, also the patterns of activation of specific signaling pathways as well as the prognostic molecular factors leading to local invasiveness are, to date, largely unknown. In this study, we used two-dimensional electrophoresi...